Herpes Simplex Virus (HSV)

What is HSV?

HSV, or herpes simplex virus, is an infection that causes herpes. Herpes can appear in different parts of the body but is most commonly seen on the mouth or genitals. In those who are immunocompromised, HSV infections are usually more severe, causing deep, painful lesions that can spread over large areas.

There are two types of herpes simplex virus,
HSV-1 and HSV-2.

What is HSV-1?
Type 1, or HSV-1, is mostly spread through oral contact and causes infections in or around the mouth. HSV-1 can also cause genital herpes through oral-genital contact. With HSV-1, the greatest risk of transmission is when there are active sores, but transmission can occur when the skin looks normal and is asymptomatic.
What is HSV-2?
Type 2, or HSV-2, is spread through sexual contact and causes genital herpes. HSV-2 can be spread even though skin may look normal and is asymptomatic.

HSV-2 increases the risk of acquiring HIV. HSV-2 is one of the most common infections in people living with HIV.

What is the current treatment for herpes simplex virus?

Oftentimes, health professionals prescribe medication like acyclovir to help treat HSV infections. However, some types of HSV do not respond to this treatment, requiring a switch to a medication called foscarnet. This is currently the only treatment option for patients who do not respond to acyclovir.

Where can I learn more?

Ask your doctor for more information about herpes simplex virus.

The following resources can help you learn more about HSV-1 and HSV-2: